{"id":12081,"date":"2026-03-17T16:50:47","date_gmt":"2026-03-17T16:50:47","guid":{"rendered":"https:\/\/medical-article.com\/?p=12081"},"modified":"2026-03-17T16:50:47","modified_gmt":"2026-03-17T16:50:47","slug":"lack-of-substantial-evidence-leads-to-fda-rejection-of-aldeyra-dry-eye-disease-drug","status":"publish","type":"post","link":"https:\/\/medical-article.com\/?p=12081","title":{"rendered":"\u2018Lack of Substantial Evidence\u2019 Leads to FDA Rejection of Aldeyra Dry Eye Disease Drug"},"content":{"rendered":"<p><a href=\"https:\/\/medcitynews.com\/2026\/03\/dry-eye-disease-aldeyra-fda-crl-reproxalap-rasp-inflammation-aldx\/\"><\/a><\/p>\n<p>Aldeyra said the FDA did not ask for another clinical trial for reproxalap in dry eye disease, but the drug\u2019s mixed record in clinical testing warrants exploration about the reasons for failure, which could identify the appropriate patients for the eye drop. AbbVie holds an option to collaborate on commercialization of reproxalap. <\/p>\n<p>The post <a href=\"https:\/\/medcitynews.com\/2026\/03\/dry-eye-disease-aldeyra-fda-crl-reproxalap-rasp-inflammation-aldx\/\">\u2018Lack of Substantial Evidence\u2019 Leads to FDA Rejection of Aldeyra Dry Eye Disease Drug<\/a> appeared first on <a href=\"https:\/\/medcitynews.com\/\">MedCity News<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>Aldeyra said the FDA did not ask for another clinical trial for reproxalap in dry eye disease, but the drug\u2019s mixed record in clinical testing warrants exploration about the reasons for failure, which could identify the appropriate patients for the eye drop. AbbVie holds an option to collaborate on commercialization of reproxalap. The post \u2018Lack&#8230;<\/p>\n","protected":false},"author":0,"featured_media":12082,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-12081","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicine"],"_links":{"self":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts\/12081"}],"collection":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=12081"}],"version-history":[{"count":0,"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts\/12081\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/media\/12082"}],"wp:attachment":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12081"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=12081"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=12081"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}