{"id":12112,"date":"2026-03-18T22:27:46","date_gmt":"2026-03-18T22:27:46","guid":{"rendered":"https:\/\/medical-article.com\/?p=12112"},"modified":"2026-03-18T22:27:46","modified_gmt":"2026-03-18T22:27:46","slug":"reframing-schizophrenia-as-a-neurodevelopmental-syndrome-the-scientific-and-social-imperative","status":"publish","type":"post","link":"https:\/\/medical-article.com\/?p=12112","title":{"rendered":"Reframing schizophrenia as a neurodevelopmental syndrome: The scientific and social imperative"},"content":{"rendered":"

That is the title of a paper published today<\/a> with co-authors Arundati Nagendra (from the Schizophrenia and Psychosis Action Alliance<\/a>), Raquelle Mesholam-Gately and Matcheri Keshavan (both at the Department of Psychiatry at Harvard Medical School). The abstract is here: <\/p>\n

Background<\/h3>\n

Schizophrenia is traditionally classified as a serious mental illness (SMI), emphasizing chronicity and disability. However, growing evidence supports that it also shows features of a neurodevelopmental syndrome, highlighting disruptions in early brain development and a diverse spectrum of trajectories.<\/p>\n

Objective<\/h3>\n

This paper proposes expanding the conceptualization of schizophrenia as both an SMI and a neurodevelopmental syndrome.<\/p>\n

Methods<\/h3>\n

We review biological, clinical, and epidemiological evidence supporting a neurodevelopmental model of schizophrenia. We then propose a three-pronged strategy to operationalize this reframing: (i) reclassification in the ICD-11 and DSM-5 as a neurodevelopmental syndrome; (ii) renaming to reflect established and evolving scientific evidence; and (iii) reshaping societal narratives so schizophrenia is understood as a developmental condition that remains modifiable.<\/p>\n

Results<\/h3>\n

A neurodevelopmental framing may advance access, quality, and equity in schizophrenia care.<\/p>\n

Conclusion<\/h3>\n

Reframing schizophrenia as a neurodevelopmental syndrome reflects modern science and, based on precedent from other countries, could catalyze systemic changes to improve care, access, and equity. <\/p>\n

You can read the full paper here<\/a><\/strong>.<\/p>","protected":false},"excerpt":{"rendered":"

That is the title of a paper published today with co-authors Arundati Nagendra (from the Schizophrenia and Psychosis Action Alliance), Raquelle Mesholam-Gately and Matcheri Keshavan (both at the Department of Psychiatry at Harvard Medical School). The abstract is here: Background Schizophrenia is traditionally classified as a serious mental illness (SMI), emphasizing chronicity and disability. However,…<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-12112","post","type-post","status-publish","format-standard","hentry","category-articles"],"_links":{"self":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts\/12112"}],"collection":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=12112"}],"version-history":[{"count":0,"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts\/12112\/revisions"}],"wp:attachment":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12112"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=12112"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=12112"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}