{"id":13001,"date":"2026-04-30T14:22:16","date_gmt":"2026-04-30T14:22:16","guid":{"rendered":"https:\/\/medical-article.com\/?p=13001"},"modified":"2026-04-30T14:22:16","modified_gmt":"2026-04-30T14:22:16","slug":"estimating-effectiveness-of-influenza-and-covid-19-vaccines-the-test-negative-design","status":"publish","type":"post","link":"https:\/\/medical-article.com\/?p=13001","title":{"rendered":"Estimating Effectiveness of Influenza and COVID-19 Vaccines: The \u201cTest-Negative\u201d Design"},"content":{"rendered":"<p>This brief summarizes the &#8220;test-negative&#8221; methodology for estimating the effectiveness of influenza and COVID-19 vaccines, noting its strengths and potential limitations. This is the design is used in a CDC-led COVID-19 vaccine study that HHS decided not to publish.<\/p>","protected":false},"excerpt":{"rendered":"<p>This brief summarizes the &#8220;test-negative&#8221; methodology for estimating the effectiveness of influenza and COVID-19 vaccines, noting its strengths and potential limitations. This is the design is used in a CDC-led COVID-19 vaccine study that HHS decided not to publish.<\/p>\n","protected":false},"author":0,"featured_media":13002,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-13001","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts\/13001"}],"collection":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=13001"}],"version-history":[{"count":0,"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts\/13001\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/media\/13002"}],"wp:attachment":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=13001"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=13001"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=13001"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}