{"id":8042,"date":"2025-09-08T20:51:13","date_gmt":"2025-09-08T20:51:13","guid":{"rendered":"https:\/\/medical-article.com\/?p=8042"},"modified":"2025-09-08T20:51:13","modified_gmt":"2025-09-08T20:51:13","slug":"summit-lung-cancer-drug-falls-short-on-key-survival-goal-in-global-study-putting-fda-approval-in-doubt","status":"publish","type":"post","link":"https:\/\/medical-article.com\/?p=8042","title":{"rendered":"Summit Lung Cancer Drug Falls Short on Key Survival Goal in Global Study, Putting FDA Approval in Doubt"},"content":{"rendered":"<p><a href=\"https:\/\/medcitynews.com\/2025\/09\/lung-cancer-summit-therapeuitcs-ivonescimab-bispecific-antibody-pd1-vegf-smmt\/\"><\/a><\/p>\n<p>Despite achieving statistically signficant improvement in progression-free survival in North American and European patients, Summit\u2019s drug ivonescimab fell short of the other Phase 3 goal measuring overall survival. It\u2019s the first Phase 3 readout for an emerging class of bispecific antibodies that treat cancer by blocking two targets, PD-1 and VEGF. <\/p>\n<p>The post <a href=\"https:\/\/medcitynews.com\/2025\/09\/lung-cancer-summit-therapeuitcs-ivonescimab-bispecific-antibody-pd1-vegf-smmt\/\">Summit Lung Cancer Drug Falls Short on Key Survival Goal in Global Study, Putting FDA Approval in Doubt<\/a> appeared first on <a href=\"https:\/\/medcitynews.com\/\">MedCity News<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>Despite achieving statistically signficant improvement in progression-free survival in North American and European patients, Summit\u2019s drug ivonescimab fell short of the other Phase 3 goal measuring overall survival. It\u2019s the first Phase 3 readout for an emerging class of bispecific antibodies that treat cancer by blocking two targets, PD-1 and VEGF. The post Summit Lung&#8230;<\/p>\n","protected":false},"author":0,"featured_media":8043,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-8042","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicine"],"_links":{"self":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts\/8042"}],"collection":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8042"}],"version-history":[{"count":0,"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts\/8042\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/media\/8043"}],"wp:attachment":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8042"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8042"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8042"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}