{"id":9300,"date":"2025-10-31T17:01:09","date_gmt":"2025-10-31T17:01:09","guid":{"rendered":"https:\/\/medical-article.com\/?p=9300"},"modified":"2025-10-31T17:01:09","modified_gmt":"2025-10-31T17:01:09","slug":"liver-complications-lead-fda-to-stop-tests-of-intellia-gene-editing-therapy-for-a-rare-disease","status":"publish","type":"post","link":"https:\/\/medical-article.com\/?p=9300","title":{"rendered":"Liver Complications Lead FDA to Stop Tests of Intellia Gene-Editing Therapy for a Rare Disease"},"content":{"rendered":"<p><a href=\"https:\/\/medcitynews.com\/2025\/10\/intellia-gene-editing-therapy-fda-clinical-hold-crispr-rare-disease-attr-ntla\/\"><\/a><\/p>\n<p>The FDA clinical hold covers two Phase 3 studies for nexiguran ziclumeran, or nex-z, an experimental gene-editing therapy for transthyretin amyloidosis. Nex-z uses the CRISPR gene-editing technology to inactivate the gene that codes for the protein driving this rare disease. <\/p>\n<p>The post <a href=\"https:\/\/medcitynews.com\/2025\/10\/intellia-gene-editing-therapy-fda-clinical-hold-crispr-rare-disease-attr-ntla\/\">Liver Complications Lead FDA to Stop Tests of Intellia Gene-Editing Therapy for a Rare Disease<\/a> appeared first on <a href=\"https:\/\/medcitynews.com\/\">MedCity News<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>The FDA clinical hold covers two Phase 3 studies for nexiguran ziclumeran, or nex-z, an experimental gene-editing therapy for transthyretin amyloidosis. Nex-z uses the CRISPR gene-editing technology to inactivate the gene that codes for the protein driving this rare disease. The post Liver Complications Lead FDA to Stop Tests of Intellia Gene-Editing Therapy for a&#8230;<\/p>\n","protected":false},"author":0,"featured_media":9301,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-9300","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicine"],"_links":{"self":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts\/9300"}],"collection":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9300"}],"version-history":[{"count":0,"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/posts\/9300\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=\/wp\/v2\/media\/9301"}],"wp:attachment":[{"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9300"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9300"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medical-article.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9300"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}