Madrigal Pharma Adds Another Genetic Medicine to Its Drug Combo Strategy in MASH

Madrigal Pharmaceuticals has licensed rights to an Arrowhead Pharmaceuticals small-interfering RNA therapy designed to address a particular genetic mutation associated with the fatty liver disease MASH. It’s Madrigal’s fourth business development deal of the past year and the company’s second one involving siRNA therapies. The post Madrigal Pharma Adds Another Genetic Medicine to Its Drug…

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CRUSHing Lab Fraud: Three Myths that Derail Real Reform

Leeza Osipenko Ekaterina Cleary Julie Egginton By JULIE EGGINGTON, EKATERINA CLEARY & LEEZA OSIPENKO When CMS issued its Request for Information under the Comprehensive Regulations to Uncover Suspicious Healthcare (CRUSH) initiative in February, it zeroed in on a long-festering problem: fraud, waste, and abuse in laboratory testing, especially in genetic and molecular diagnostics. The laboratory…

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Does biosimilar entry reduce cost for patients?

Biosimilars aim to be lower cost options for biologic therapies after loss of exclusivity. A key question is whether these cost savings get passed through to patients via lower out-of-pocket costs. A paper by Dayer et al. (2026) aims to answer this question using 2011-2023 Merative MarketScan Commercial claims data. The authors observed: …significant patient…

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Is the Atrium-WakeMed Merger Already Hitting a Wall?

A proposed merger between Atrium Health and WakeMed Health is facing an early delay, with county commissioners having postponed a key vote over transparency concerns. State officials are warning the deal could hurt competition and drive up healthcare costs in the Raleigh area. The post Is the Atrium-WakeMed Merger Already Hitting a Wall? appeared first…

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