2025 Books of the Year

As I do every year, here are the books I read and enjoyed this year. Non-fiction. How to Read a Book: The Classic Guide to Intelligent Reading by Mortimer Adler. This is probably not the most ‘fun’ book I read for the year, but it is the one that is likely to have the biggest…

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Rural Health Providers Hit by $100K Trump Visa Fee

More than 30 people have applied for a lab technician job at West River Health Services in Hettinger, North Dakota, a thousand-person town in the rural southwestern part of the state. Because they aren’t U.S. citizens, they would each need a visa. West River and other companies used to pay up to $5,000 in fees…

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How do CMS negotiated prices compare to value?

That is the question asked in a recent Health Affairs Forefront article by Peter Neumann, Josh Cohen, Sean Sullivan and Feng Xie. They compare the CMS negotiated prices for Initial Price Applicability Year (IPAY) 2027 against value-based prices (using QALYs) from the Tufts Cost-Effectiveness Analysis (CEA) Registry. The authors found that cost-effectiveness estimates varied among…

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Let’s get moving on AI-discovered treatments

By STEVEN ZECOLA Recursion Pharmaceuticals announced results today for one its AI-discovered treatments. I was pleased to see the large, sustained reduction in polyps attributable to its treatment for Familial Adenomatous Polyposis.  Recursions’ oral medication will be viewed by the traditional scientific and regulatory community as “promising”. On the other hand, I was disappointed not…

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