
What is the PICOSI framework?
When conducting evidence synthesis, many individuals use the PICO framework. PICO stands for population; intervention; comparator(s); and outcome. This helps to describe the research question that the evidence synthesis aims to answer. However, recently Remiro‐Azócar (2024) proposed PICOSI framework. PICOSI stands for: PopulationInterventionComparator(s)OutcomesSummary effect measure; Intercurrent events In fact, Canada’s Drug Agency’s (CDA) recent draft…