Startup Booster Therapeutics Launches to Usher In Next Wave of Protein-Degrading Drugs

Booster Therapeutics’ small molecules activate the 20S proteasome, a component of cells that gets rid of misfolded proteins. Parkinson’s and Alzheimer’s are potential disease targets for the startup, which launched with $15 million in seed financing. The post Startup Booster Therapeutics Launches to Usher In Next Wave of Protein-Degrading Drugs appeared first on MedCity News.

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Gilead’s New $250M Drug R&D Pact Adds Contenders in the Hunt for Hot Inflammation Target

Gilead Sciences is acquiring LEO Pharma’s oral small molecule inhibitors of STAT6, a protein key to two validated inflammation pathways. Other STAT6 drug developers include Kymera Therapeutics and Sanofi-partnered Recludix Pharma, which is presenting this week during the J.P. Morgan Healthcare Conference. The post Gilead’s New $250M Drug R&D Pact Adds Contenders in the Hunt…

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July 4, 1862

By MIKE MAGEE When I asked my brilliant literary agent, Jill Kneerim, when I would know that my book proposal  was ready for submission, she replied directly, “It will be ready when I say it is ready.” Eleven months later, in April, 2018, she finally green lit the project, and two weeks after that, in…

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Can Precision Psychiatry Be Delivered Remotely? The Limits and Opportunities of Telehealth in Interventional Care

How much of precision interventional psychiatry can actually happen remotely, and where does the model hit a wall? The answer is potentially more nuanced than the conventional framing suggests. The post Can Precision Psychiatry Be Delivered Remotely? The Limits and Opportunities of Telehealth in Interventional Care appeared first on MedCity News.

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Factors That Increase Utilization Management Risk

That is the title of a new paper published in the American Journal of Managed Care (AJMC) with co-authors Jacob Fajnor, Shurui Zhang, and Donald Nichols. The abstract is below. Objectives: To (1) develop a metric that quantitatively measures the risk that utilization management (UM) policies pose to patients and (2) measure the relationship between…

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