BioCryst’s $700M Astria Acquisition Gives It a Shot to Beat Larger Rivals in Rare Disease HAE

BioCryst Pharmaceuticals’ Astria Therapeutics acquisition brings navenibart, a drug in Phase 3 testing for the rare disease hereditary angioedema. The injectable antibody has the potential to match the efficacy of the blockbuster Takeda Pharmaceutical drug that currently dominates the market, but with less burdensome dosing that could encourage HAE patients to switch. The post BioCryst’s…

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About Half of Adults with ACA Marketplace Coverage are Small Business Owners, Employees, or Self-Employed

This analysis estimates that 48% of adults under age 65 with individual market coverage are either employed by a small business with fewer than 25 workers, self-employed entrepreneurs, or small business owners. Because the vast majority of this coverage is purchased through the Affordable Care Act (ACA) Marketplaces, changes to the ACA, including the expiration…

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The Pill Patients Saved

It reduced cravings, dulled alcohol’s “buzz,” and carried no risk of addiction. By every measure, naltrexone should have immediately become a major triumph. Instead, it flopped because the institutions charged with treating addiction refused to use it. Now considered a gold standard, it survived because patients and communities kept it alive. The post The Pill Patients…

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The Future of Drug Discovery is 3D

Improving the identification and validation of disease-specific drug targets in a cell-type and patient-specific manner early on will not only reduce the failure rate and cost that is so inherent in current drug development processes but also allow the development of more effective precision medicines, improving patient outcomes. The post The Future of Drug Discovery…

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