Side Effects are Limiting GLP-1 Drug Efficacy: How Can Personalization Offer a Solution?

By integrating digitization and machine learning, there is an opportunity to deliver personalized care to all patients and scale precision dosing with minimal physician involvement, maximizing the effectiveness and accessibility of these drugs. The post Side Effects are Limiting GLP-1 Drug Efficacy: How Can Personalization Offer a Solution? appeared first on MedCity News.

Read More

How should you price new therapies when the standard of care is not cost effective?

Let’s say that there is a very severe disease—let’s call it horriblitis—with significant impacts on patient morbidity and mortality.  The only available treatment for horriblitis is drug called BlackPill.  BlackPill improves health outcomes by 1 QALY over best supportive care (BSC), but costs $500,000 over the patient’s lifetime.   While not cost effective by traditional standards,…

Read More

Sleep: Watch This Space

By MIKE MAGEE In case you’ve missed it, sleep is all the rage in neurosciences these days. They are fast at work rebranding it “the brain’s rinse cycle.”  The brain, protectively encased in an unyielding bony casing, lacks the delicate lymphatic system that transports used body metabolites to breakdown and extraction sites in all other parts…

Read More

Ventyx Bio Cardiovascular Drug’s Phase 2 Results Set Up Talks With a Big Pharma Firm

In a placebo-controlled mid-stage study, Ventyx Biosciences’ oral NLRP3 inhibitor led to rapid and sustained reductions in levels of a protein that’s an indicator of cardiovascular disease risk. The brain-penetrating properties of this once-daily pill also have potential applications addressing inflammation that drives neurodegenerative disorders. The post Ventyx Bio Cardiovascular Drug’s Phase 2 Results Set…

Read More

Stick to the Science

By KIM BELLARD A year ago I wrote about disturbing news from the Pew Research Center that trust in science, and in scientists, had fallen since the pandemic. I am slightly relieved to report that a new follow-up study by Pew indicates that trust is up slightly – but still way below where they were…

Read More