Sarepta CEO: ‘We Have, I Believe, a Very Laudable History of Being Extraordinarily Transparent’

Sarepta Therapeutics knew about the death of a patient treated with its experimental gene therapy for a type of limb-girdle muscular dystrophy, but said nothing public for a month. Financial analysts lambasted Sarepta executives for failing to disclose the fatality when the company announced a restructuring that includes stopping work on this limb-girdle program. The…

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Readers Offer Solo Agers Support and Reflect on Ancestors

Letters to the Editor is a periodic feature. We welcome all comments and will publish a selection. We edit for length and clarity and require full names. Solo Agers, Join the Crowd! Enjoyed your panel discussion (Watch: ‘Going It Alone’ — A Conversation About Growing Old in America, Dec. 12). I am 85, retired at 55. Traveled (birding)…

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Does PBM Market Share Vary by Payer Type?

A paper by Qato et al. (2024) quantifies the degree of of pharmacy benefit manager (PBM) market concentration. Across all payer types, the PBM market was highly concentrated, with an HHI [Herfindahl Hirschman Index (HHI)] of 1972…the HHI was lowest in commercial insurance (1940), with 90 PBM participants, and highest in Medicare Part D (2399),…

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Trump Restores Title X Funding for Two Anti-Abortion States — While Wiping It Out Elsewhere

The Trump administration quietly restored federal family planning money to Tennessee and Oklahoma, despite court rulings that the states weren’t entitled to funds because they refused to provide women information about terminating pregnancies or abortion referrals on request. The decision by the Department of Health and Human Services to restore millions of dollars for the…

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“Precision Med Has Evolved as Badly As I Expected” And OtherTakeaways From Former FDA Commissioner At PMWC

Robert Califf addressed a range of issues, including AI, lack of nutrition resources at the FDA and how he evaluates the progress of precision medicine at the Precision Medicine World Conference in Silicon Valley. The post “Precision Med Has Evolved as Badly As I Expected” And OtherTakeaways From Former FDA Commissioner At PMWC appeared first…

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Augmenting Brain Power: Real-World Data, Advanced Analytics, and the Future of Clinical Trials

The application of AI technology is part of a carefully orchestrated effort dependent on human intelligence, and the collaboration of physicians, disease-specific specialists, nurses, data scientists, and technologists. Done right, these efforts can lead to profound benefits, and offer a promising future for clinical research and patient care. The post Augmenting Brain Power: Real-World Data, Advanced…

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Watch: What Is Medicaid, Again?

Republicans in Congress have suggested big cuts to Medicaid. But what exactly is it? Medicaid, the state-federal health insurance program for people with low incomes or disabilities, is integral to the U.S. health care system. It keeps hospitals and other providers afloat, provides a key source of federal funds to states, and helps provide health…

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